Creatinine Levels in Blood (Serum Creatinine)

Creatinine in blood is also called serum creatinine. It is a chemical waste molecule that is generated from muscle metabolism. Therefore it is closely related to the amount of muscles. It will not easily affected by diet. A minority of creatinine in blood comes from protein that people have eaten, which do not affect creatinine in blood greatly. Creatinine in blood is one of the important clinical indicators of renal function.

What does it indicate if creatinine level is high in blood?

Creatinine level in blood indicates the degree of kidney parenchyma damage clearly, but it is not a sensitive indicator. It is due to the reason that creatinine level in blood begins to decline when GFR decreases to one-third of normal people’s. Then creatinine level in blood will increase. Kidneys have strong metabolic capacity. This is why people will not have feelings about it when damage of kidney function is not serious.

What are the reasons of increase of creatinine level in blood?

1. Fatigue can cause temporary increase of creatinine level in blood.

2. If concurrent infection including cold, pneumonia, intestinal tract infection and urinary tract infection presents in people with renal dysfunction, creatinine level in blood can increase in short time.

3. Body loses more water can be one of the causes. Fever, little water intake will cause pachemia when you are in diuretic phase. Reducing of blood flow volume of kidney could cause increase of creatinine level in blood.

4. People with kidney diseases take some medication that is toxic to kidney. Creatinine level in blood can increase and sometimes it can not be reversed.

5. The relapse of kidney diseases, Oliguria even anuria may present, acute renal dysfunction can be accompanied. Then creatinine level in blood can increase.

6. If there is hypertension, creatinine level in blood can increase gradually if your blood pressure is not controlled well and moderate or large quantity of proteinuria (urine protein is more than 1 gram or even 1.5 gram) presents for a long time.

If your creatinine level in blood has increased, don't panic, sometimes it will decrease itself. But it is better to have a physical examination and get the diagnosis in time. In some cases, timly treatment of high level of creatinine in blood is suggested to prevent serious conditions.

learn more:What Does Creatinine 4.8 Mean And How to Lower It