▲ Pain of renal area is a major symptom. It usually refers to constriction or dull pain, sharp pain, sometimes abdominal pain or tenderness. The pain may become serious after doing manual work, long-time work or sitting. The pain may also result from the internal haemorrhage of kidneys, kidney stones movement or infection.
▲ Nephromegaly. Due to inconsonant development of bilateral kidneys condition, their sizes are different. In the late stage of Polycystic Kidney Disease, the two kidneys can fill the whole enterocoelia. There are many cysts on the surface of kidneys, which are irregular in outline and solid in the texture.
▲ Blood in the urine (hematuria). Approximately half of children with Polycystic Kidney Disease present microscopic hematuria, and some have paroxysmal gross hematuria caused by the burst of cyst wall blood vessels. When kidneys are infected, there will be obvious pyuria, severe hematuria and back pain accompanied with fever.
▲ High blood pressure (hypertension). This is a common sign of children Polycystic Kidney Disease. Almost half of patients have high blood pressure before the serum creatinine increases, which is caused by the stress of cysts on neighboring tissues, inducing rennin, angiotensin and the response of aldosterone.
▲ Urinary tract infection. More than half of Polycystic Kidney Disease patients appear urinary tract infection, and is more prone to women than men.
Besides, other symptoms also include cysts in other organs, mass in abdomen, kidney stones and urine protein and do on. Patient should receive effective treatment to prevent the disease progress into Renal Failure.
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